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  • 產(chǎn)品名稱：CFB 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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簡單介紹：
CFB 抗原（重組蛋白）深獲顧客信賴外，更帶給顧客喜悅和滿足，公司員工亦因此找到工作及生活的意義，將緊跟經(jīng)營管理和科學(xué)技術(shù)發(fā)展的步伐，提升和加強公司的市場競爭力，同心協(xié)力，盡展創(chuàng)意，致力于可持續(xù)發(fā)展、向社會盡責(zé)的企業(yè)宗旨。
詳情介紹：
中文名稱： CFB 抗原（重組蛋白）

英文名稱： CFB Antigen (Recombinant Protein)

別     名：  complement factor B; BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14

相關(guān)類別： 抗原

儲     存：  冷凍（-20℃）

概     述

Fusion protein corresponding to a region derived from 615-764 amino acids of human CFB

技術(shù)規(guī)格

Full name:

complement factor B

Synonyms:

BF; FB; BFD; GBG; CFAB; CFBD; PBF2; AHUS4; FBI12; H2-Bf; ARMD14

Swissprot:

P00751

Gene Accession:

BC004143

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes complement factor B, a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease which associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. This gene localizes to the major histocompatibility complex (MHC) class III region on chromosome 6. This cluster includes several genes involved in regulation of the immune reaction. Polymorphisms in this gene are associated with a reduced risk of age-related macular degeneration. The polyadenylation site of this gene is 421 bp from the 5' end of the gene for complement component 2.






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