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  • 產(chǎn)品名稱:CISH 抗原(重組蛋白)

  • 產(chǎn)品型號:1mg
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價格:3580
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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簡單介紹:
CISH 抗原(重組蛋白)深獲顧客信賴外,更帶給顧客喜悅和滿足,公司員工亦因此找到工作及生活的意義,將緊跟經(jīng)營管理和科學(xué)技術(shù)發(fā)展的步伐,提升和加強公司的市場競爭力,同心協(xié)力,盡展創(chuàng)意,致力于可持續(xù)發(fā)展、向社會盡責(zé)的企業(yè)宗旨。
詳情介紹:
中文名稱: CISH 抗原(重組蛋白)

英文名稱: CISH Antigen (Recombinant Protein)

別     名:  cytokine inducible SH2 containing protein; CIS; G18; SOCS; CIS-1; BACTS2

相關(guān)類別: 抗原

儲     存:  冷凍(-20℃)

概     述

Fusion protein corresponding to a region derived from 59-258 amino acids of human CISH

技術(shù)規(guī)格

Full name:

cytokine inducible SH2 containing protein

Synonyms:

CIS; G18; SOCS; CIS-1; BACTS2

Swissprot:

Q9NSE2

Gene Accession:

BC031590

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene contains a SH2 domain and a SOCS box domain. The protein thus belongs to the cytokine-induced STAT inhibitor (CIS), also known as suppressor of cytokine signaling (SOCS) or STAT-induced STAT inhibitor (SSI), protein family. CIS family members are known to be cytokine-inducible negative regulators of cytokine signaling. The expression of this gene can be induced by IL2, IL3, GM-CSF and EPO in hematopoietic cells. Proteasome-mediated degradation of this protein has been shown to be involved in the inactivation of the erythropoietin receptor. Multiple transcript variants encoding different isoforms have been found for this gene.






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