英文名稱： RGS6 Antigen (Recombinant Protein)
別 名： regulator of G protein signaling 6; GAP; S914; HA117
儲(chǔ) 存： 冷凍（-20℃）
相關(guān)類別： 抗原
概 述
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Full name: |
regulator of G protein signaling 6 |
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Synonyms: |
GAP; S914; HA117 |
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Swissprot: |
P49758 |
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Gene Accession: |
BC113572 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the RGS (regulator of G protein signaling) family of proteins, which are defined by the presence of a RGS domain that confers the GTPase-activating activity of these proteins toward certain G alpha subunits. This protein also belongs to a subfamily of RGS proteins characterized by the presence of DEP and GGL domains, the latter a G beta 5-interacting domain. The RGS proteins negatively regulate G protein signaling, and may modulate neuronal, cardiovascular, lymphocytic activities, and cancer risk. Many alternatively spliced transcript variants encoding different isoforms with long or short N-terminal domains, complete or incomplete GGL domains, and distinct C-terminal domains, have been described for this gene, however, the full-length nature of some of these variants is not known. |
