中文名稱: PFKM 抗原(重組蛋白)
儲(chǔ) 存: 冷凍(-20℃)
Full name: |
phosphofructokinase, muscle |
Synonyms: |
GSD7; PFK1; PFKA; PFKX; PFK-1; ATP-PFK; PPP1R122 |
Swissprot: |
P08237 |
Gene Accession: |
BC021203 |
Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
Expression system: |
Escherichia coli |
Tags: |
His tag C-Terminus, GST tag N-Terminus |
Background: |
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. |