英文名稱: Anti-PTPN22 rabbit polyclonal antibody
別 名: LYP; PEP; LYP1; LYP2; PTPN8
相關(guān)類別: 一抗
儲(chǔ) 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: PTPN22
反應(yīng)種屬: Human, Mouse
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
This gene encodes of member of the non-receptor class 4 subfamily of the protein-tyrosine phosphatase family. The encoded protein is a lymphoid-specific intracellular phosphatase that associates with the molecular adapter protein CBL and may be involved in regulating CBL function in the T-cell receptor signaling pathway. Mutations in this gene may be associated with a range of autoimmune disorders including Type 1 Diabetes, rheumatoid arthritis, systemic lupus erythematosus and Graves' disease. Alternatively spliced transcript variants encoding distinct isoforms have been described. |
Applications: |
ELISA, IHC |
Name of antibody: |
PTPN22 |
Immunogen: |
Fusion protein of human PTPN22 |
Full name: |
protein tyrosine phosphatase, non-receptor type 22 (lymphoid) |
Synonyms: |
LYP; PEP; LYP1; LYP2; PTPN8 |
SwissProt: |
Q9Y2R2 |
ELISA Recommended dilution: |
2000-5000 |
IHC positive control: |
Human thyroid cancer and human ovarian cancer |
IHC Recommend dilution: |
30-150 |