英文名稱: Anti-PTRH2 rabbit polyclonal antibody
別 名: BIT1; PTH2; CFAP37; CGI-147
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃)
宿 主: Rabbit
抗 原: PTRH2
反應(yīng)種屬: Human, Mouse
標 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
PTRH2 (peptidyl-tRNA hydrolase 2), also known as BIT1 (Bcl-2 inhibitor of transcription 1), is a 179 amino acid mitochondrial protein. During apoptosis, PTRH2 is released from the mitochondia to the cytoplasm. Once in the cytoplasm, PTRH2 regulates the function of two transcriptional regulators, TLE5 and TLE1, thereby promoting caspase-independent cell death. It is also believed that the natural substrate for PTRH2 may be petidyl-tRNAs, which leave the ribosomes during protein synthesis. |
Applications: |
ELISA, WB, IHC |
Name of antibody: |
PTRH2 |
Immunogen: |
Fusion protein of human PTRH2 |
Full name: |
peptidyl-tRNA hydrolase 2 |
Synonyms: |
BIT1; PTH2; CFAP37; CGI-147 |
SwissProt: |
Q9Y3E5 |
ELISA Recommended dilution: |
2000-10000 |
IHC positive control: |
Human breast cancer |
IHC Recommend dilution: |
10-50 |
WB Predicted band size: |
19 kDa |
WB Positive control: |
Raji, Jurkat, 231, hepg2 and K562 cells |
WB Recommended dilution: |
1000-5000 |