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  • 產(chǎn)品名稱：RGS14 抗原（重組蛋白）

  • 產(chǎn)品型號：100ug
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：800
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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詳情介紹：
中文名稱： RGS14 抗原（重組蛋白）

英文名稱： RGS14 Antigen (Recombinant Protein)

別     名：  regulator of G protein signaling 14

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 302-566 amino acids of human RGS14

技術(shù)規(guī)格

Full name:

regulator of G protein signaling 14

Swissprot:

O43566

Gene Accession:

BC014094

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a member of the regulator of G-protein signaling family. This protein contains one RGS domain, two Raf-like Ras-binding domains (RBDs), and one GoLoco domain. The protein attenuates the signaling activity of G-proteins by binding, through its GoLoco domain, to specific types of activated, GTP-bound G alpha subunits. Acting as a GTPase activating protein (GAP), the protein increases the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.







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