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  • 產(chǎn)品名稱：SPACA3 抗原（重組蛋白）

  • 產(chǎn)品型號(hào)：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價(jià)格：3580
  • 產(chǎn)品庫(kù)存：35
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中文名稱： SPACA3 抗原（重組蛋白）

英文名稱： SPACA3 Antigen (Recombinant Protein)

別     名：  sperm acrosome associated 3; CT54; LYC3; LYZL3; SLLP1; ALLP17; 1700025M08Rik

相關(guān)類別： 抗原

儲(chǔ)     存：  冷凍（-20℃） 

概     述

Fusion protein corresponding to a region derived from 1-123 amino acids of human SPACA3

技術(shù)規(guī)格

Full name:

sperm acrosome associated 3

Synonyms:

CT54; LYC3; LYZL3; SLLP1; ALLP17; 1700025M08Rik

Swissprot:

Q8IXA5

Gene Accession:

BC029867

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

SPACA3 (sperm acrosome associated 3), also known as sperm lysozyme-like protein 1, lysozyme-like protein 3, lysozyme-like acrosomal sperm-specific secretory protein ALLP-17, cancer/testis antigen 54 (CT54), LYC3, SPRASA or LYZL3, is a 215 amino acid protein that participates in the fusion and adhesion of sperm and egg plasma membrane during fertilization. Identified as a novel cancer/testis antigen in hematologic malignancies, SPACA3 has the ability to elicit B-cell immune responses in patients with cancer and is considered a potential target for immunotherapy. A member of the glycosyl hydrolase 22 family which is expressed in testis, placenta and epididymis, SPACA3 exists as two alternatively spliced isoforms; SPACA3 isoform 1 is a single-pass type II membrane protein of the sperm acrosome whereas SPACA3 isoform 2 is a secreted protein. Sperm surface membrane protein that may be involved in sperm-egg plasma membrane adhesion and fusion during fertilization. It could be a potential receptor for the egg oligosaccharide residue N-acetylglucosamine, which is present in the extracellular matrix over the egg plasma membrane. The processed form has no detectable bacteriolytic activity in vitro.







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