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  • 產(chǎn)品名稱：SPRTN 抗原（重組蛋白）

  • 產(chǎn)品型號：1mg
  • 產(chǎn)品廠商：通蔚生物
  • 產(chǎn)品價格：3580
  • 產(chǎn)品庫存：35
  • 產(chǎn)品文檔：
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中文名稱： SPRTN 抗原（重組蛋白）

英文名稱： SPRTN Antigen (Recombinant Protein)

別     名：  SprT-like N-terminal domain; DVC1; PRO4323; spartan; C1orf124

儲     存：  冷凍（-20℃）

相關(guān)類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-243 amino acids of human SPRTN

技術(shù)規(guī)格

Full name:

SprT-like N-terminal domain

Synonyms:

DVC1; PRO4323; spartan; C1orf124

Swissprot:

Q9H040

Gene Accession:

BC015740

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

The protein encoded by this gene may play a role in DNA repair during replication of damaged DNA. This protein recruits valosin containing protein (p97) to stalled DNA replication forks where it may prevent excessive translesional DNA synthesis and limit the number of DNA-damage induced mutations. It may also be involved in replication-related G2/M-checkpoint regulation. Deficiency of a similar protein in mouse causes chromosomal instability and progeroid phenotypes. Mutations in this gene have been associated with Ruijs-Aalfs syndrome (RJALS). Alternatively spliced transcript variants have been identified.







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