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  • 產品名稱：SPRY2 抗原（重組蛋白）

  • 產品型號：100ug
  • 產品廠商：通蔚生物
  • 產品價格：800
  • 產品庫存：35
  • 產品文檔：
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中文名稱： SPRY2 抗原（重組蛋白）

英文名稱： SPRY2 Antigen (Recombinant Protein)

別     名：  sprouty RTK signaling antagonist 2; IGAN3; hSPRY2
 
儲     存：  冷凍（-20℃）

相關類別： 抗原

概     述

Fusion protein corresponding to a region derived from 1-315 amino acids of human SPRY2

技術規(guī)格

Full name:

sprouty RTK signaling antagonist 2

Synonyms:

IGAN3; hSPRY2

Swissprot:

O43597

Gene Accession:

BC015745

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein.








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