中文名稱: 兔抗MDM2多克隆抗體
英文名稱: Anti-MDM2 rabbit polyclonal antibody
別 名: HDMX; hdm2; ACTFS
相關(guān)類別: 一抗
儲 存: 冷凍(-20℃) 避光
宿 主: Rabbit
抗 原: MDM2
反應(yīng)種屬: Human
標(biāo) 記 物: Unconjugate
克隆類型: rabbit polyclonal
技術(shù)規(guī)格
Background: |
MDM2, a ubiquitin ligase for p53, plays a central role in regulation of the stability of p53 . Akt-mediated phosphorylation of MDM2 at Ser166 and Ser186 increases its interaction with p300, allowing MDM2-mediated ubiquitination and degradation of p53 . Phosphorylation of MDM2 also blocks its binding to p19ARF, increasing the degradation of p53 . |
Applications: |
WB |
Name of antibody: |
MDM2 |
Immunogen: |
Synthetic peptide of human MDM2 |
Full name: |
MDM2 oncogene, E3 ubiquitin protein ligase |
Synonyms: |
HDMX; hdm2; ACTFS |
SwissProt: |
Q00987 |
WB Predicted band size: |
90 kDa |
WB Positive control: |
293 and Hela cells |
WB Recommended dilution: |
500-1000 |