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  • 產(chǎn)品名稱:NCOA4 抗原(重組蛋白

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中文名稱: NCOA4 抗原(重組蛋白)

英文名稱: NCOA4 Antigen (Recombinant Protein)

別     名:  nuclear receptor coactivator 4; RFG; ELE1; PTC3; ARA70

儲(chǔ)     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概      述

Fusion protein corresponding to a region derived from 1-200 amino acids of human NCOA4

技術(shù)規(guī)格

Full name:

nuclear receptor coactivator 4

Synonyms:

RFG; ELE1; PTC3; ARA70

Swissprot:

Q13772

Gene Accession:

BC012736

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

This gene encodes an androgen receptor coactivator. The encoded protein interacts with the androgen receptor in a ligand-dependent manner to enhance its transcriptional activity. Chromosomal translocations between this gene and the ret tyrosine kinase gene, also located on chromosome 10, have been associated with papillary thyroid carcinoma. Alternatively spliced transcript variants have been described. Pseudogenes are present on chromosomes 4, 5, 10, and 14.






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