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  • 產(chǎn)品名稱:PLEKHG6 抗原(重組蛋白)

  • 產(chǎn)品型號:100ug
  • 產(chǎn)品廠商:通蔚生物
  • 產(chǎn)品價(jià)格:800
  • 產(chǎn)品庫存:35
  • 產(chǎn)品文檔:
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詳情介紹:


中文名稱: PLEKHG6 抗原(重組蛋白)

英文名稱: PLEKHG6 Antigen (Recombinant Protein)

別     名:  pleckstrin homology domain containing, family G (with RhoGef domain) member 6; MyoGEF

儲     存:  冷凍(-20℃)

相關(guān)類別: 抗原

概      述

Fusion protein corresponding to a region derived from 161-353 amino acids of human PLEKHG6

技術(shù)規(guī)格

Full name:

pleckstrin homology domain containing, family G (with RhoGef domain) member 6

Synonyms:

MyoGEF

Swissprot:

Q3KR16

Gene Accession:

BC105961

Purity:

>85%, as determined by Coomassie blue stained SDS-PAGE

Expression system:

Escherichia coli

Tags:

His tag C-Terminus, GST tag N-Terminus

Background:

PLEKHG6 functions as a guanine nucleotide exchange factor activating the small GTPase RHOA, which, in turn, induces myosin filament formation. It activates RHOG but not activate RAC1, or to a much lower extent than RHOA and RHOG. Part of a functional unit, involving MyoGEF, MYH10 and RHOA, at the cleavage furrow to advance furrow ingression during cytokinesis. In epithelial cells, required for the formation of microvilli and membrane ruffles on the apical pole. Along with EZR, required for normal macropinocytosis.





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